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Two investigators (Yanni Yao and Nairong Liu) independently extracted data using a standardized template, capturing the following: (1) Basic information of the included studies: Title, first author, publication year, study design (e.g., RCT, cohort), country, and population profile (e.g., T2D with/without CKD): (2) basic characteristics of the research subjects, including Age, sex/gender distribution, sample size per group, and diagnostic criteria for T2D and comorbid conditions
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